Atopic dermatitis and DNA methylation at birth: findings from epigenome-wide meta-analyses

Meta-analyses results from "Atopic dermatitis and DNA methylation at birth: findings from epigenome-wide meta-analyses". This data contains summary statistics from 12 meta-analyses of EWAS of atopic dermatitis (AD) using DNA methylation measured using the Illumina Infinium HumanMethylation450 BeadChip. Details on the analyses can be found in the paper. 

Each of the files are tab-separated with the following column names (description in brackets):

CpG

Beta (the effect estimate)

SE (standard error)

P (P value)

Direction (Direction of effect within each cohort)

Het_ISq (I2 value of heterogeneity)

Het_P (P value from Cochran’s Q-test for heterogeneity)

The files are named in the following way: `AD-PHENOTYPE_MODEL_COHORT-STRAT.tsv`

AD-PHENOTYPE: childhood, early-onset, or persistent.
MODEL: Model A, B, or C (see paper for details)
COHORT-STRAT: If the cohorts were stratified in anyway here is where it will be indicated. DD = AD was defined by doctor diagnosis only, DD-R = AD was defined by doctor diagnosis and/or rash symptoms, HR = AD was defined using the Hanifin-Rajka criteria. 

For example, the file `childhood_model-C_DD.tsv` contains the summary statistics from the meta-analysis of EWAS of AD within cohorts that defined AD using doctor diagnosis only.