The Brazilian Initiative on Precision Medicine (BIPMed)

The development of precision medicine strategies requires prior knowledge of the genetic background of the target population. However, despite the availability of data from admixed Americans within large reference population databases, we cannot use these data as a surrogate for that of the Brazilian population. This lack of transferability is mainly due to differences between ancestry proportions of Brazilian and other admixed American populations. To address the issue, a coalition of research centres created the Brazilian Initiative on Precision Medicine (BIPMed), an initiative of five Research Innovation and Dissemination Centers (RIDCs) supported by FAPESP. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from peripheral blood samples from 340 reference individual. The Brazilian Research Institute for Neuroscience and Neurotechnology (BRAINN), Center for Computational Science and Engineering (CCES), Center for Research in Cell Therapy (CTC), Center for Research on Inflammatory Diseases (CRID), Obesity and Comorbidities Research Center (OCRC)