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Neutrophils stimulation with AVP promote IL36G release

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP476043
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We found that neutrophils were homing back to bone marrow and induced myelopoiesis after AVP treatment.This study investigated how neutrophils promoted HSC differentiation by comparing the expression of genes between control and AVP treatment neutrophils.We demonstrated that AVP treatment increased the expression of a variety of cytokine genes, especially IL36G, and the augmentation of bone marrow myelopoiesis involves IL36G-IL1RL2 axis. Overall design: We performed transcriptional profiling using RNA-seq in flow cytometry sorted neutrophils from blood of control and AVP-treated mice
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2024-12-18
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