Reviewer-access data and code for: Pre-existing peripheral CD8+ central memory T cell activation predicts severe toxicity and limited benefit from immune checkpoint blockade in melanoma

This Zenodo repository contains the processed data, source data, analysis scripts, and raw cytometry files required for confidential editorial and peer review of the manuscript: “Pre-existing peripheral CD8+ central memory T cell activation predicts severe toxicity and limited benefit from immune checkpoint blockade in melanoma.” Contents include: 1. Processed proteomics and cytometry datasets used for figure generation (CAN-26-1887_code_and_data_for_review.zip) 2. R scripts and notebooks required to reproduce the analyses and figures (CAN-26-1887_code_and_data_for_review.zip) 3. Raw CyTOF/FCS data files from this study (HCI001_raw_fcs_data.zip, HCI002_raw_fcs_data.zip, Switzerland1_CD8.rda, Switzerland2_CD8.rda, Switzerland3_CD8.rda) The repository is being shared for confidential editorial and peer-review purposes only prior to publication. Redistribution prohibited prior to publication. For questions regarding the data, please contact:Tian-Gen Chang ([e-mail])