Crystal structure of human FPPS in complex with [({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)
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Crystal structure of human FPPS in complex with [({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid) Descriptor: Farnesyl pyrophosphate synthase, GLYCEROL, MAGNESIUM ION, ... Authors: Rodionov, D, Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2014-03-18 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. PLoS ONE, 12, 2017
人类法尼基焦磷酸合酶(Farnesyl pyrophosphate synthase,FPPS)与[({4-[4-(环丙氧基)苯基]吡啶-2-基}氨基)亚甲基]双膦酸复合物的晶体结构
晶体结构描述:法尼基焦磷酸合酶、甘油、镁离子……
作者:Rodionov D、Park J、Lin Y.-S、Tsantrizos Y.S、Berghuis A.M.
存档日期:2014-03-18
发布日期:2015-04-15
最后修改日期:2023-09-20
实验方法:X射线衍射(2.18埃)
引用文献:《与人类法尼基焦磷酸合酶结合的苯基氨基吡啶双膦酸盐的晶体学与热力学表征》,《公共科学图书馆·综合》(PLoS ONE),第12卷,2017年
创建时间:
2014-03-18



