The impact of COVID-19 on the health of physicians, nurses, and other health care workers [C19-HCW, study data contributed to the CITF Databank]

Background: Healthcare workers are at high risk for infection from SARS-CoV-2 due to close contact on the front lines. Regardless of infection, these individuals are prone to impacts to their mental health. Aims of the CITF study: The study aimed to determine the extent of participants that had antibodies to SARS-CoV-2 and understand the impact of risk factors on participants’ health during the pandemic. It also aimed to evaluate their mental health status and identify workplace practices and community supports that could be improved to increase safety and alleviate stress (Note: mental health data not shared with CITF Databank [1]). Methods: Healthcare workers (physicians, nurses, health care aids, and personal support workers) across British Columbia, Alberta, Ontario, and Quebec were recruited into a cohort study via advertisements through professional organizations. Participants completed a screening interview and a baseline questionnaire. Participants who tested positive after their blood sample were placed into a nested cohort study. At follow-up visits every 3 months, blood samples were collected, and exposure questionnaires and mental health assessments were administered. A blood sample was also collected 4 months post-vaccine. Contributed dataset contents: The datasets include 3005 participants who completed baseline questionnaires between April 2020 and November 2020. 87% of participants gave one or more blood samples for SARS-CoV-2 serology between September 2020 and June 2022 (in follow-up visits). Variables include data in the following areas of information: demographics (age, gender, race-ethnicity and indigeneity, province, occupation), general health (smokes; asthma, lung disease, or immune compromised diagnosis; height and weight; flu vaccine), and longitudinal follow-up for COVID infections (dates of positive PCR or RAT tests, hospitalization, outcome and scale for impact of infection on everyday life), SARS-CoV-2 vaccination, and serology. [1]: Please contact original study team for mental health data背景：由于在一线开展密切接触操作，医护人员（healthcare workers）面临极高的新型冠状病毒（SARS-CoV-2）感染风险。即便未发生感染，这类人群也极易出现心理健康相关问题。 CITF研究（CITF study）目标：本研究旨在明确受试者体内新型冠状病毒（SARS-CoV-2）抗体的阳性水平，探究疫情期间各类风险因素对受试者健康的影响；同时评估其心理健康状态，识别可优化的职场操作与社区支持方案，以提升工作安全性并缓解工作压力。（注：心理健康数据未共享至CITF数据库[1]） 方法：本研究通过专业机构发布招募广告，招募不列颠哥伦比亚省、阿尔伯塔省、安大略省与魁北克省的医护人员，包含医师、护士、医疗辅助人员及个人支持护工，参与队列研究。受试者需完成筛查访谈与基线调查问卷。经血液检测呈阳性的受试者将被纳入巢式队列研究（nested cohort study）。每3个月开展一次随访，期间采集血液样本，并完成暴露史问卷与心理健康评估。此外，研究团队还会在受试者完成疫苗接种4个月后采集其血液样本。 贡献数据集内容：本数据集涵盖2020年4月至2020年11月期间完成基线问卷的3005名受试者。其中87%的受试者在2020年9月至2022年6月的随访周期内，提供了一份或多份用于新型冠状病毒（SARS-CoV-2）血清学检测的血液样本。数据集包含以下多维度信息变量：人口统计学数据（年龄、性别、种族族裔与原住民身份、所在省份、职业）、基础健康状况（吸烟史、哮喘/肺部疾病/免疫功能低下诊断史、身高体重、流感疫苗接种史）、新冠感染纵向随访数据（新冠病毒聚合酶链反应（PCR）或快速抗原检测（RAT）阳性日期、住院情况、感染转归及感染对日常生活影响的量表评分）、新型冠状病毒（SARS-CoV-2）疫苗接种史与血清学检测数据。 [1]：心理健康数据需联系原研究团队获取。