Genome-wide epigenome mapping in human induced pluripotent cells in WT and KMT2CKO cells. [ChIP-Seq]

KMT2C is a histone methyltransferase that mono-methylates lysine four at enhancer regions. This study compares the histone modification pattern between WT and KMT2C KO cells and further evaluates their functional validation by applying the invitro hematopoietic differentiation protocol. Examination of 4 different histone modifications in WT and KMT2CKO hIPSCs cells.