BindingDB Entry 50034613: Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

Small molecule binding data for protein Cyclin-dependent kinase 4, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Glycogen synthase kinase-3, MAP kinase ERK2, MAP kinase-activated protein kinase 2, Macrophage colony stimulating factor receptor, Mitogen-activated protein kinase 10, PKC alpha and beta-2, Platelet-derived growth factor receptor beta, Protein kinase C (PKC), Protein kinase C alpha type, Pyruvate dehydrogenase kinase 4 (PDK4), RAF serine/threonine protein kinase, Receptor tyrosine-protein kinase erbB-4 (HER4), Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase LCK, Tyrosine-protein kinase SYK, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O60674, P00533, P04626, P05771, P06240, P07333, P09619, P10721, P11802, P12931, P15056, P17252, P28482, P35968, P36888, P43405, P49137, P49841, P53350, P53779, Q02763, Q05513, Q08881, Q15303, and Q16654