Pulmonary ILC2s differentially depend on epithelial cell- and lymphatic endothelial cell-IL-7 in acute and chronic airway inflammations

This study reveals the role of IL-7 produced by pulmonary stromal cells for the maintenance and activation of group 2 innate lymphoid cells (ILC2s) in the lung. Transcriptional profiling of lung ILC2s from IL-7-flox/flox (control) and SPC-Cre; IL-7-flox/flox mice本研究揭示了肺基质细胞产生的IL-7在肺部维持并激活2型先天淋巴细胞（group 2 innate lymphoid cells，ILC2s）中的作用，并对来自IL-7-flox/flox（对照组）及SPC-Cre; IL-7-flox/flox小鼠的肺部ILC2s开展了转录谱分析。