Specific inhibition of p300-HAT alters Global Gene Expression and Repress HIV replication

ChEBI2010-06-11 更新2026-07-21 收录

HIV复制抑制

表观遗传调控

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Specific inhibition of p300-HAT alters Global Gene Expression and Repress HIV replication

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2010-06-11

Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation

组蛋白修饰与肿瘤发生

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In this study, our results support a functional divergence between H3K36me2 and H3K36me3 and their non-redundant roles in H3K36M-driven oncogenesis Overall design: 17 ChIP-seq samples, 3 RNA-seq sampl

NIAID Data Ecosystem50

Identification of introduced and stably inherited DNA methylation variants in soybean associated with soybean cyst nematode parasitism [RNA-seq]

大豆抗线虫研究

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Methylome changes mediated by the soybean cyst nematode resistance gene GmSHMT08 Overall design: Examining the changes in the transcriptome of two nearly isogenic lines (TN09-16 and TN09-29) under soy

NIAID Data Ecosystem10

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

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甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Epigenetic basis for monocyte dysfunction in acute-on-chronic liver failure and alcoholic hepatitis [RNA-seq]

肝病相关单核细胞功能障碍

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BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

NIAID Data Ecosystem10

Transcriptional Dynamics of Skeletal Muscle in Obesity (PRJCA023478)

肥胖相关转录组学

表观遗传调控

Skeletal muscle is a metabolically active organ, but it remains largely unexplored in obesity. Here, we used diet-induced mice as obesity model to investigate the effect of obesity on muscle transcrip

NIAID Data Ecosystem00

Specific inhibition of p300-HAT alters Global Gene Expression and Repress HIV replication

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