Recombination walking: genetic selection of clones from pooled libraries of yeast artificial chromosomes by homologous recombination.
收藏PubMed Central1993-09-01 更新2026-05-16 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC47299/
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资源简介：
Recombination walking is based on the genetic selection of specific human clones from a yeast artificial chromosome (YAC) library by homologous recombination. The desired clone is selected from a pooled (unordered) YAC library, eliminating labor-intensive steps typically used in organizing and maintaining ordered YAC libraries. Recombination walking represents an efficient approach to library screening and is well suited for chromosome-walking approaches to the isolation of genes associated with common diseases. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1993-09-01
