The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2

The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Thomsen, M, Neudegger, T, Thieulin-Pardo, G, Blaesse, M, Costanzi, E, Steinbacher, S, Plotnikov, N.V, Dominguez, C, Iyer, R.R, Wilkinson, H.A, Monteagudo, E, Haque, T.S, Prasad, B.C, Finley, M, Boudet, J, Vogt, T.F, Felsenfeld, D.P. Deposit date: 2023-12-01 Release date: 2025-06-11 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (2.67 Å) Cite: The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3 To Be Published结合DNA的人类MutSβ（MSH2_E749A/MSH3）晶体结构，处于经典错配结合构象，且MSH2亚基结合了腺苷-5'-二磷酸（ADP） 组分描述：1,2-乙二醇、腺苷-5'-二磷酸、氯离子…… 作者：Thomsen, M, Neudegger, T, Thieulin-Pardo, G, Blaesse, M, Costanzi, E, Steinbacher, S, Plotnikov, N.V, Dominguez, C, Iyer, R.R, Wilkinson, H.A, Monteagudo, E, Haque, T.S, Prasad, B.C, Finley, M, Boudet, J, Vogt, T.F, Felsenfeld, D.P. 提交日期：2023-12-01 发布日期：2025-06-11 最近修改日期：2025-07-09 实验方法：X射线衍射（分辨率2.67埃） 引用：结合DNA的人类MutSβ（MSH2/MSH3）晶体结构，处于经典错配结合构象，且MSH2与MSH3亚基均结合了腺苷-5'-二磷酸（ADP），待发表