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miRNA expression profiling in PANC-1 cells treated with TGFb and additional PDAC lines

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE88756
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miRNAs are known to be involved in PDAC tumourigenesis. However, not many have been investigated in the context of TGFb-induced EMT. To identify novel miRNAs involved in this response, we performed a miRNA profiling study in PANC-1 cells treated with TGFb and additional PDAC lines with epithelial or mesenchymal characteristics. miRNA expression profiling was performed using a panel of 4 increasingly mesenchymal cell lines: BxPC-3 cells, PANC-1 cells treated with vehicle or TGFb (5nM) for 72h and S2-007 cells. Three biological replicates for each condition were used for expression analysis.
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2023-02-21
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