Structure of C5a bound human C5aR1 in complex with Go (Composite map)

Structure of C5a bound human C5aR1 in complex with Go (Composite map) Descriptor: Antibody fragment - ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... Authors: Yadav, M.K, Yadav, R, Maharana, J, Banerjee, R, Shukla, A.K, Gati, C. Deposit date: 2023-02-07 Release date: 2023-10-18 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023结合C5a的人源C5a受体1（C5aR1）与Go蛋白形成的复合物结构（复合电子密度图） 描述：抗体片段：ScFv16（单链可变片段16）、过敏毒素C5a（C5a anaphylatoxin）、C5a过敏毒素趋化受体1（C5a anaphylatoxin chemotactic receptor 1）等 作者：Yadav, M.K.、Yadav, R.、Maharana, J.、Banerjee, R.、Shukla, A.K.、Gati, C. 提交日期：2023-02-07 发布日期：2023-10-18 最后更新日期：2024-11-20 实验方法：电子显微镜（分辨率3.21埃） 引用文献：《补体受体上过敏毒素的结合、激活及信号偏倚的分子基础》，《细胞》（Cell），第186卷，2023年