IL-13Ra1-mediated signaling regulates ABC expansion and lupus pathogenesis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206012
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资源简介：
ABCs are an emerging B cell subset that aberrantly expand in SLE. ABC generation and differentiation exhibit marked sexual dimorphism and TLR7 engagement is a key contributor to these sex differences. ABC generation is also controlled by IL-21 and its interplay with IFNg and IL-4. Here we investigated whether IL-13Ra1, an X-linked receptor that transmits IL-4/IL-13 signals, can regulate ABCs and lupus pathogenesis. 7 samples: 4 DKO, 3 IL13KO+DKO contributor: HSS Genomics Research Center
创建时间：
2022-06-16
