PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex with Z44585777

PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex with Z44585777 Descriptor: DIMETHYL SULFOXIDE, N-phenylpyrrolidine-1-carboxamide, Protease 3C Authors: Lithgo, R.M, Fairhead, M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Godoy, A.S, Marples, P.G, Ni, X, Tomlinson, C.W.E, Thompson, W, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. Deposit date: 2023-08-24 Release date: 2023-11-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals. Biorxiv, 2024

PanDDA分析工作组提交数据集——肠道病毒D68 3C蛋白酶（Enterovirus D68 3C Protease）与Z44585777的共晶结构。描述项：二甲基亚砜（DIMETHYL SULFOXIDE）、N-苯基吡咯烷-1-甲酰胺、3C蛋白酶（Protease 3C）。作者：Lithgo, R.M、Fairhead, M、Koekemoer, L、Aschenbrenner, J.C、Balcomb, B.H、Godoy, A.S、Marples, P.G、Ni, X、Tomlinson, C.W.E、Thompson, W、Wild, C、Fearon, D、Walsh, M.A、von Delft, F。提交日期：2023-08-24；发布日期：2023-11-29；最后修改日期：2024-10-16。研究方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.51埃（Å）。引用文献：《柯萨奇病毒A16型2A蛋白酶的晶体片段筛选为广谱抗肠道病毒药物研发提供新契机》（Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals），发表于BioRxiv，2024年。