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PERSONALIZED MULTIDISCIPLINARY POSTOPERATIVE CARE ALGORITHM FOR NEWBORNS WITH CONGENITAL INTESTINAL OBSTRUCTION: A PROSPECTIVE STUDY

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Zenodo2026-03-23 更新2026-05-26 收录
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Objective: To evaluate the clinical effectiveness of a personalized multidisciplinary postoperative care algorithm in newborns undergoing surgery for congenital intestinal obstruction (CIO). Background: Congenital intestinal obstruction represents a major surgical and neonatal care challenge worldwide. Despite technological advances, postoperative morbidity and prolonged recovery remain significant concerns. Emerging evidence supports individualized multidisciplinary care models to optimize outcomes in this vulnerable population. Methods: A prospective controlled study was conducted between 2022 and 2024, including 82 newborns diagnosed with CIO. Patients were allocated into two comparable groups: Group I (n=42) received standard postoperative care, and Group II (n=40) was managed with a personalized multidisciplinary algorithm comprising guided thermoregulation, structured early nutrition, targeted infection prevention, and comprehensive clinical monitoring. Primary outcomes included time to stabilization of vital functions, frequency of postoperative complications, duration of hospitalization, mechanical ventilation, and overall clinical improvement. Comparative statistical analysis was performed using Student’s t-test and χ² test. Results: Baseline demographic and clinical variables were statistically similar between groups. Group II demonstrated significantly faster stabilization of body temperature, respiratory function, and hemodynamic parameters (p<0,01). Infectious complications and feeding intolerance occurred less frequently in Group II (p<0,05). Hospital stay and duration of mechanical ventilation were significantly reduced in Group II (p<0,001). Overall clinical improvement ≥75% was significantly higher in Group II (p<0.05). Mortality differences showed a favorable trend but did not reach statistical significance. Conclusions: Implementation of a personalized multidisciplinary postoperative care algorithm significantly improves clinical recovery and reduces complication rates in newborns with CIO. These findings support the adoption of individualized postoperative strategies in neonatal surgical practice.

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Zenodo
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2026-03-23
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