Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine

Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine Descriptor: 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, MAGNESIUM ION, Nucleoside 2-deoxyribosyltransferase Authors: Tang, P, Harding, C.J, Czekster, M.C. Deposit date: 2023-07-11 Release date: 2024-02-21 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis, 14, 2024

结合氯法拉滨（Clofarabine）的来自热色球藻（Chroococcidiopsis thermalis）PCC 7203的核苷2'-脱氧核糖基转移酶E88Q突变体结构。组成描述：2-氯-9-(2-脱氧-2-氟-β-D-阿拉伯呋喃糖基)-9H-嘌呤-6-胺、镁离子、核苷2'-脱氧核糖基转移酶。作者：Tang P、Harding C.J、Czekster M.C.。提交日期：2023-07-11；发布日期：2024-02-21；最后修改日期：2024-11-13。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.23埃（Å）。引用文献：《嗜热2'-脱氧核糖核苷/核糖核苷转移酶反应坐标快照》，发表于《ACS催化》（Acs Catalysis），2024年，第14卷。