Antibody Inhibition of Human T-Cell Responses to Bacterial Superantigens.

aFL = full-length native Mab. All data show antibody inhibition of toxin-induced IFNγ release, relative to toxin only-treated PBMCs that act as a control. Data represent the mean of quadruplicate readings resulting from two separate experiments.bNot tested, due to weak cross-reactivity by ELISA.cPercent inhibition given in parentheses at the highest concentration (1500 nM for Fab and 1000 nM for FL Mab) of weak-performing antibodies.dPolyclonal anti-SEB from human sera, affinity-purified against SEB.eControl human Fab against SEA that did not cross-react with SEB by ELISA.