Application of neutrophil-to-lymphocyte-monocyte ratio in predicting mortality risk in adult patients with septic shock: A retrospective cohort study conducted at a single center

Data collection: Patients were categorized into survival and death groups based on their 28-day survival status during hospitalization. The following clinical information of the patients in both groups was collected: (1) general data, including sex, age, body mass index, source of infection, and comorbidities assessed using the Elixhauser comorbidity index (ECI);[14][15] (2) the laboratory results within 24 h of intensive care unit (ICU) admission included blood cell analysis indexes, such as neutrophil count (N), monocyte count (M), lymphocyte count (L), hemoglobin (Hb), platelet count (PLT), and blood biochemical indexes, such as blood lactic acid (Lac), total bilirubin (TBIL), blood urea nitrogen (BUN), creatinine (Cr), oxygenation index (P/F), C-reactive protein (CRP), and procalcitonin (PCT). (3) The Glasgow Coma Scale (GCS) score, quick Sequential Organ Failure Assessment (qSOFA) score, Sequential Organ Failure Assessment (SOFA) score, and Acute Physiology and Chronic Health Evaluation II (APACHE II) score were calculated according to the worst value of each index within 24 h after admission failure assessment; and (4) interventions conducted within 24 h after admission to ICU were as follows: mechanical ventilation, maximum norepinephrine equivalent within 24 h (NEEmax),[16] and renal replacement therapy, among others.