Fungal opportunistic pathogens colonize various environments, from plants and wood to human and animal tissue. Regarding human pathogens, one great challenge during contrasting niche occupation is the

NIAID Data Ecosystem50

A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome

隐球菌致病机制

蛋白质棕榈酰化

Cryptococcus neoformans is an opportunistic yeast that kills over 625,000 people yearly through lethal meningitis. Host phagocytes serve as the first line of defense against this pathogen, but fungal

NIAID Data Ecosystem30

Proteome characterization of Paracoccidioides lutzii conidia by using label free proteomics

病原真菌蛋白质组学

微生物毒力因子分析

Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin America. The PCM is a systemic disease caused by the thermo dimorphic fungus Paracoccidioides spp, which can exist as mycelia and yeast form

NIAID Data Ecosystem50

Transcriptomic response of Cryptococcus neoformans to ecologically relevant nitrogen concentrations

隐球菌致病机制

真菌转录组响应

We examine the transcriptomic response of Cryptococcus neoformans to two different ecologically relevant nitrogen concentrations. Our data revealed that low nitrogen conditions modulate the expression

NIAID Data Ecosystem40

Secretome profiling of Cryptococcus neoformans

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