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Cleavable β‑Cyanoethyl Isocyanide in the Ugi Tetrazole Reaction

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https://figshare.com/articles/dataset/Cleavable_Cyanoethyl_Isocyanide_in_the_Ugi_Tetrazole_Reaction/3817029
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资源简介:
β-Cyanoethyl isocyanide is introduced as a cleavable isocyanide in the Ugi tetrazole reaction. Eleven examples are described that exhibit a broad scope and are obtained in good overall yields. The obtained 1H-tetrazole scaffold is an important bioisostere for carboxylic acids, and the method described here is a valuable alternative route to known procedures.
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2016-10-03
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