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Human RORM-NM-3t+ CD34+ cells are lineage-specified progenitors of group 3 RORM-NM-3t+ innate lymphoid cells

ChEBI2014-11-25 更新2026-07-21 收录

免疫细胞发育

先天淋巴样细胞谱系

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-63197 数据链接链接失效反馈

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Human RORM-NM-3t+ CD34+ cells are lineage-specified progenitors of group 3 RORM-NM-3t+ innate lymphoid cells

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创建时间：

2014-11-25

免疫细胞发育

单细胞转录组学

T cells develop in the thymus from multipotent lymphoid precursors. During this gradual differentiation process thymocytes go through several decision points, before they fully mature into conventiona

NIAID Data Ecosystem70

Data_Sheet_4_Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development.PDF

免疫细胞发育

单细胞转录组学

Intrathymic differentiation of T lymphocytes begins as early as intrauterine stage, yet the T cell lineage decisions of human fetal thymocytes at different gestational ages are not currently understoo

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Single cell RNA-seq (10X Chromium 3') analysis of the DN1 population from E15.5 embryonic thymus of the 5x polychromILC mice. Single cell RNA-seq (10X Chromium 3') analysis of the DN1 population from E15.5 embryonic thymus of the 5x polychromILC mice

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单细胞转录组学

ILC2 contribute to immune homeostasis, protective immunity and tissue repair. However, an understanding of the microenvironmental factors and transcriptional circuits that support development of these

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CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development

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CRISPRi基因编辑

The SLAM family receptors contribute to diverse aspects of lymphocyte biology and signal via the small adaptor molecule SAP. Mutations affecting SAP lead to X-linked lymphoproliferative syndrome Type

NIAID Data Ecosystem50

Negative regulation of lymphoid specification by the transcription factor TAL1

免疫细胞发育

转录因子调控

Lymphoid primed multipotent progenitors are a subset of MPPs that are undergoing specification to the lymphoid and myeloid cell fates. The transcription factors Lyl1 and E2A are both essential for the

NIAID Data Ecosystem30

Human RORM-NM-3t+ CD34+ cells are lineage-specified progenitors of group 3 RORM-NM-3t+ innate lymphoid cells

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