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High-Throughput Screening for Myelination Promoting Compounds Using Human Stem Cell-derived Oligodendrocyte Progenitor Cells Identifies Novel Targets

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE223599
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High-Throughput Screening for Myelination Promoting Compounds Using Human Stem Cell-derived Oligodendrocyte Progenitor Cells Identifies Novel Targets The reporter hESCs were differentiated to OPCs by following the protocol described above. On day 30 of differentiation, neurospheres were plated on a 6-well culture dish to facilitate OPC migration from the plated spheres. 3 wells of day 80 differentiating cultures were treated DMSO as control and two wells each were treated with different small molecules for 10 days
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2023-04-29
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