Left Ventricular Function in Control, TAC alone and together with IMD supplementation treated Mice (mean±s.e.m., n = 10).

LVP, left ventricle (LV) pressure; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic pressure; dP/dtmax, maximal value of the first derivative of LV pressure; dP/dtmin, minimal value of the first derivative of LV pressure; ESV, end-systolic volume; EDV, End-diastolic volume; SV, stroke volume; CO, cardiac output; EF, ejection fraction; AE, arterial elastance; SW, stroke work. CON, control; TAC and TAC+IMD mean mice received transverse aortic constriction treatment without and with IMD treatment for 4 weeks, respectively.
*P<0.05 and **P<0.01 vs the control;
#P<0.05,
##P<0.01 vs TAC alone 4 weeks group. TAC, transverse aortic constriction; IMD, intermedin.