five

Hypoxia blocks round spermatids deformation through downregulation of Axsl2 gene

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA784762
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GC1 (a mouse derived spermatogonia cell) and GC2 (a mouse derived spermatocyte cell) cells were exposed to 21% oxygen concentration and 1% oxygen concentration for 48 hours respectively, and then ChIP-seq method was used to analyze the binding of ASXL2 (Additional sex combs like-2) and EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit) to downstream target gene promoters.
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2021-11-30
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