CRN-6 can partially substitute for NUC-1 in mediating degradation of DNA in ventral cord apoptotic cells.
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aAll strains except nuc-1(e1392) were in unc-119(ed3); nuc-1(e1392) background. smIs170 and smIs172 are Pnuc-1nuc-1::gfp transgenic lines. smIs173 and smIs175 are Pnuc-1crn-6::gfp transgenic lines. smIs209-smIs211 are Pnuc-1crn-7::gfp transgenic lines. smIs195 and smIs199 are Pcrn-6nuc-1::gfp transgenic lines (see Table S1 for details)
bN. P. C. indicates the number of ventral cord pycnotic nuclei, which were scored at different larval stages. “n” indicates the number of animals scored. The data shown are mean±SD.
cAll gut staining was scored at L3–L4 stages. “n” indicates the number of animals scored.
dsmEx4085 is an extrachromosomal transgene array containing Pnuc-1crn-7::gfp and Pmyo-2gfp.
创建时间：
2009-10-07
