Shedding dynamics, genetic variation, and reassortment of heterosubtypic influenza secondary infection in pigs

Whole genome sequencing of swine influenza virus samples collected from challenged pigs after exposure to pigs infected by another subtype of influenza virus. The objective of this study was to evaluate the extent of heterologious subtype influenza secondary infection at the individual pig level and how it impacts virus diversity and reassortment in pigs under an experimental co-infection model.