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High-throughput RNAi screening for genes essential for senecent cell viability

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145414
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We carried out the analysis using human skin fibroblast HCA2 (MJ90) cells. Cells were induced to be senescent cells by treatment with nutlin3a + RO3306. The cells were infected with lentiviruses enocoding shRNA against human genes (DECIPHER Human Modules 1-3). As a result, we found some gene candidates involved in senecent cell viability. shRNA library sceening of senescent HCA2 cells induced by nutlin3a + RO3306.
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2020-02-19
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