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Mapping degradation signals and pathways in a eukaryotic N-terminome [data set]

B2FIND2026-04-11 收录

蛋白质降解

N-末端组学

数据链接：

https://b2find.eudat.eu/dataset/6fe92e71-6757-54ce-977c-16a7cde5969f 数据链接链接失效反馈

官方服务：

资源简介：

Data accompanying the paper "Mapping degradation signals and pathways in a eukaryotic N-terminome".

应用场景：

神经退行性疾病

蛋白质降解

Defects of autophagy-lysosomal protein degradation are thought to contribute to the pathogenesis of several neurodegenerative diseases, and the accumulation of aggregation prone proteins such as MAPT/

DataCite Commons2021-01-18 更新170

A Cryptic K48 Ubiquitin Chain Binding Site on UCH37 is Required for its Role in Proteasomal Degradation

蛋白质降解

泛素化组学

Source data

Mendeley Data2024-03-27 更新80

Chemically induced cereblon (CRBN) degradation: efficacy of recruiting CRBN in comparison to VHL

蛋白质降解

药物发现

As small molecule degrader technology has developed, it has raised the question of whether E3 ligases could be induced to self-ubiquitinate. To examine this question, we generated six CRBN-CRBN degrad

NIAID Data Ecosystem50

Source file for all images (p53-Fbw7a)

分子生物学

蛋白质降解

Raw data of the paper on the degradation of p53 by Fbw7a

DataCite Commons2025-06-01 更新90

Additional file 12 of TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L

基因集富集分析

蛋白质降解

Additional file 12: Table S5 TRIM25-CIC-ATXN1L gene set enrichment analysis. A) Gene set enrichment analysis of upregulated discordant DE genes shared between TRIM25 vs CIC and TRIM25 vs ATXN1L. B) Ge

Figshare2020-10-29 更新50

Mapping degradation signals and pathways in a eukaryotic N-terminome [data set]

资源简介：

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