Structure of rat beta-arrestin 1 bound to allosteric inhibitor

Structure of rat beta-arrestin 1 bound to allosteric inhibitor Descriptor: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, Beta-arrestin-1,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, ... Authors: Pakharukova, N, Kahsai, A.W, Masoudi, A, Lefkowitz, R.J. Deposit date: 2024-09-17 Release date: 2025-01-22 Last modified: 2025-07-16 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Small-molecule modulation of beta-arrestins. Biorxiv, 2025结合变构抑制剂的大鼠β-抑制蛋白1（beta-arrestin 1）结构。变构抑制剂描述符：(1β,6β,7β,8α,9β,10α,13α,14R,16β)-1,6,7,14-四羟基-7,20-环氧贝壳杉烷-15-酮、β-抑制蛋白1、可溶性细胞色素b562（soluble cytochrome b562）、抗BRIL Fab重链等。作者：Pakharukova N、Kahsai A.W、Masoudi A、Lefkowitz R.J. 提交日期：2024-09-17 发布日期：2025-01-22 最后修改日期：2025-07-16 实验方法：电子显微镜（分辨率3.47埃） 引用文献：《Small-molecule modulation of beta-arrestins》，BioRxiv，2025