NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE
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NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE Descriptor: 1-(4-CARBOXY-2-GUANIDINOPENTYL)-5,5'-DI(HYDROXYMETHYL)PYRROLIDIN-2-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Finley, J.B, Atigadda, V.R, Duarte, F, Zhao, J.J, Brouillette, W.J, Air, G.M, Luo, M. Deposit date: 1999-02-15 Release date: 1999-02-27 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J.Mol.Biol., 293, 1999
《流感病毒神经氨酸酶新型芳香类抑制剂与活性位点保守残基及水分子的选择性相互作用》
描述物：1-(4-羧基-2-胍基戊基)-5,5'-二(羟甲基)吡咯烷-2-酮、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、钙离子(Calcium Ion)等
作者：Finley, J.B.、Atigadda, V.R.、Duarte, F.、Zhao, J.J.、Brouillette, W.J.、Air, G.M.、Luo, M.
提交日期：1999-02-15
发布日期：1999-02-27
最后修改日期：2024-10-30
实验方法：X射线衍射(X-RAY DIFFRACTION)，分辨率2.4埃(Å)
引用文献：《流感病毒神经氨酸酶新型芳香类抑制剂与活性位点保守残基及水分子的选择性相互作用》，《分子生物学杂志(J.Mol.Biol.)》，293卷，1999年
创建时间：
1999-02-15
