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Crystal Structure of CARD9 coiled-coil K156-K214 bound to Compound 1

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Protein Data Bank Japan2026-04-29 更新2026-06-30 收录
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Crystal Structure of CARD9 coiled-coil K156-K214 bound to Compound 1 Descriptor: (2P)-2-(1-benzyl-3-phenyl-1H-pyrazol-4-yl)-5-chloro-1-[(1R)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-1H-1,3-benzimidazole-6-carboxylic acid, Caspase recruitment domain-containing protein 9 Authors: Raymond, D.D, Lemke, C.T. Deposit date: 2024-03-04 Release date: 2025-03-12 Last modified: 2026-04-29 Method: X-RAY DIFFRACTION (2.726 Å) Cite: Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity. Cell, 189, 2026
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2024-03-04
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