Molecular snapshots of drug release from tubulin: 10 microseconds after photoactivation.

Molecular snapshots of drug release from tubulin: 10 microseconds after photoactivation. Descriptor: Azo-Combretastatin A4 (trans), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... Authors: Wranik, M, Weinert, T, Standfuss, J. Deposit date: 2022-02-18 Release date: 2023-02-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography. Nat Commun, 14, 2023

微管蛋白药物释放的分子快照：光激活后10微秒时刻。描述符：偶氮康普他汀A4（Azo-Combretastatin A4，反式）、钙离子、设计型锚蛋白重复蛋白（Designed Ankyrin Repeat Protein，DARPIN）D1等。作者：Wranik M、Weinert T、Standfuss J。提交日期：2022-02-18；发布日期：2023-02-22；最后修改日期：2024-02-07。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.2埃）。引用：《利用时间分辨串行晶体学观测光药理药物从微管蛋白中的释放过程》，《自然-通讯》（Nat Commun），第14卷，2023年。