Marine metabolomics: measurement of metabolites in seawater by gas chromatography mass spectrometry (Cell culture sampling)

One of the major bottlenecks in describing marine ecosystems is characterizing the metabolome of seawater, as salt prevents metabolite analysis. We present SeaMet, a method that can detect hundreds of metabolites in less than one ml of seawater and quantifies them down to nano-molar levels using gas chromatography-mass spectrometry. Our method provides a major advance in marine metabolomics by enabling the unbiased analysis of primary metabolites across saltwater habitats.

Cell culture sampling is reported in the current study.
Method development is reported in MTBLS826
The effect of salt and water on metabolite detection is reported in MTBLS839
Environmental sampling is reported in MTBLS844
Method quantification is reported in MTBLS848
Solid phase extraction is reported in MTBLS849