Pairs of unlinked loci showing significant non-random associations.

Six of the seven linkage groups of the N. crassa linkage maps incorporated markers involved in non-random associations with markers on different linkage groups.1A is NcA-Louisiana; C is NcC-India.2Expected haplotype counts are calculated from observed allele frequencies as follows: For a haplotype with allele i at locus 1 and allele j at locus 2, the expected genotypic count, Nijexpected, is piqjNtotal, where p and q are allele frequencies at locus 1 and locus 2, respectively, and Ntotal is the number of progeny that were genotyped at loci 1 and 2.3D′ is D/Dmax, where D = P11P22−P12P21 and Dmax is p1q2 or p2q1, whichever is smaller; P is genotypic frequency, while p and q are allelic frequencies.4Unbiased P values for the Fisher exact test of genetic disequilibrium are estimated in using a Markov chain. P values reflect Bonferroni multiple test correction for the 21 nonidentical pairs of linkage groups.