Crystal structure of CYP154C5 from Nocardia farcinica in complex with 5alpha-Androstan-3-one

Crystal structure of CYP154C5 from Nocardia farcinica in complex with 5alpha-Androstan-3-one Descriptor: (5~{S},8~{S},9~{S},10~{S},13~{S},14~{S})-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one, CHLORIDE ION, Cytochrome P450 monooxygenase, ... Authors: Rodriguez, A, Kluenemann, T, Blankenfeldt, W, Schallmey, A. Deposit date: 2019-12-11 Release date: 2020-11-18 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2 Å) Cite: CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate Modifications and Protein Engineering*. Chembiochem, 22, 2021

鼻疽诺卡氏菌（Nocardia farcinica）来源的CYP154C5与5α-雄甾烷-3-酮（5alpha-Androstan-3-one）结合的晶体结构。数据集描述项：(5S,8S,9S,10S,13S,14S)-10,13-二甲基-1,2,4,5,6,7,8,9,11,12,14,15,16,17-十四氢环戊烷并[a]菲-3-酮、氯离子（CHLORIDE ION）、细胞色素P450单加氧酶（Cytochrome P450 monooxygenase）等。作者：Rodriguez A、Kluenemann T、Blankenfeldt W、Schallmey A。提交日期：2019年12月11日，发布日期：2020年11月18日，最后修改日期：2024年10月23日。检测方法：X射线衍射（X-RAY DIFFRACTION），分辨率2埃（Å）。引用文献：*CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate Modifications and Protein Engineering*，刊载于《化学生物化学》（Chembiochem）2021年第22卷。