Clinical Development of mRNA and Traditional Vaccines

This dataset provides a comprehensive, structured repository of clinical vaccine trials, capturing a wide spectrum of research from the early 2000s through 2026 in the United States of America. It serves as a detailed ledger of the global vaccine development landscape, tracking trial lifecycle, regulatory milestones, and associated epidemiological data. Variables NCT_Number: Unique identifier assigned to the protocol by the sponsor Study_Title: The title of the clinical study, corresponding to the title of the protocol Disease_Condition: Disease or health condition studied in the clinical trial Vaccine_Type: Type of vaccine platform evaluated (ARNm, Traditional) Applicant: Entity that submitted the biologics license application to the FDA Trial_Enrollment: Number of participants enrolled or planned for enrollment Trial_Start_Date: Date when the clinical study began (YYYY-MM-DD) Trial_Finish_Date: Date when the study was completed (YYYY-MM-DD) Trial_Duration_Months: Total study duration in month calculated from start to completion date Trial_Phase: Development phase of the clinical trial (Phase 1–4) Biologic_Name: Name of the FDA-licensed biological product FDA_Proper_Name: Official nonproprietary (scientific) name of the biologic FDA_Proprietary_Name: Brand (trade) name under which the product is marketed FDA_Marketing_Status: Current regulatory marketing status of the biologic (Licensed, Voluntarily Revoked) FDA_Licensure: Official FDA approval (licensure) information for the biologic product YYYY_incidence: Annual disease incidence rate Trial_Status: Current status of a clinical trial, showing whether it is recruiting, active, completed, suspended, etc.