Single-Cell RNA-Seq Analysis of Metastasis-Primary Tumor Dissimilarity in a Patient with Gastrointestinal Neuroendocrine Cancer. Single-Cell RNA-Seq Analysis of Metastasis-Primary Tumor Dissimilarity in a Patient with Gastrointestinal Neuroendocrine Cancer

A 58 year old female diagnosed with a metastic GI-NET underwent resection of primary tumor as well as several metastatic lesions. We performed scRNA-seq of the primary tumor and one lesion from the liver metastasis to perform comparitive analysis between the primary and metastic tumor compositions. Overall design: scRNAseq was performed on theprimary small intestinal neuroendocrine tumor and its matched liver metastasis simultaneously.