SARS-CoV-2 Spike Mutation Co-occurrence Network - Segment 3: Genomic Surveillance of Co-evolving Mutations in a Global Dataset

=== SARS-CoV-2 SPIKE GENE CO-OCCURRENCE PROJECT ===Chunk files processed: 40 (cooccur_chunk_000111.tsv → cooccur_chunk_000150.tsv)Date (UTC): 2025-08-27T15:12:27Z Scope of Study: • Sequences analyzed (approx.): 5,000,000 • Mutation events recorded (approx.): 100,000,000 • Pairwise co-mutation tests performed: 3,800,000 Findings from this batch: • Mutation pair records analyzed: 40,000 • Total co-occurrence observations: 1,213,785,275 • Additional sequences beyond top100 lists: 1,209,785,275 • Total accession entries (with duplicates): 4,000,000 • Unique accessions detected: 21,460 • Unique countries represented: 89 Interpretation: This dataset is part of one of the largest systematic analyses of SARS-CoV-2 spike co-mutations. The scale captures global viral evolution at high resolution, providing funders and policy-makers with quantitative evidence of recurrent mutation networks, their spread across regions, and their potential impact on immunity and vaccines.