Stimulating Disfunctional Bowel before Ileostomy Closure
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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2756349
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Interventions: This study will be a two arms open-label randomized controlled clinical trial. Patients will be recruited from a public teaching hospital specializing in oncological surgery and all procedures will be performed in this same hospital (Hospital Municipal Vila Santa Catarina, São Paulo, Brazil). Considering a 17% risk difference for adynamic ileus rate difference, the calculation of the minimum sample N is 52 patients in each study arm, considering alpha (two-sided) 0.05 and beta 0.2.;H02.403.810.208;E04.210.338.508
Primary outcome(s): It is expected that after ileostomy closure surgery in patients undergoing stimulation of the dysfunctional intestinal loop, there is an improvement in intestinal transit (lower rate of adynamic ileus), verified through clinical reports provided by patients;It is expected that after ileostomy closure surgery in patients undergoing stimulation of the dysfunctional intestinal loop, patients will present a good acceptance of the diet early, that is, it is expected that they will not present symptoms with nausea or vomiting when eating.;It is expected that after ileostomy closure surgery in patients undergoing stimulation of the dysfunctional intestinal loop, patients will have early evacuation, that is, 72 hours after the surgical procedure.
创建时间:
2022-08-15



