datset of "Networks and genes modulated by posterior hypothalamic stimulation in patients with aggressive behaviours: Analysis of probabilistic mapping, normative connectomics, and atlas-derived transcriptomics of the largest international multi-centre dataset"

This dataset accompanies the manuscript:
"Networks and genes modulated by posterior hypothalamic stimulation in patients with aggressive behaviours: Analysis of probabilistic mapping, normative connectomics, and atlas-derived transcriptomics of the largest international multi-centre dataset."
DOI: (https://doi.org/10.1101/2022.10.29.22281666)

by

Flavia Venetucci Gouveia1,2,3*†,Jürgen Germann4,5†, Gavin JB Elias4,5, Alexandre Boutet4,6, Aaron Loh4,5, Adriana Lucia Lopez Rios7,8, Cristina V Torres Diaz9, William Omar Contreras Lopez10,11, Raquel CR Martinez3,12, Erich T Fonoff13, Juan C Benedetti-Isaac14,  Peter Giacobbe 2,15,16, Pablo M Arango Pava17, Han Yan5,18, George M Ibrahim5, 18,19,20, Nir Lipsman2,5,15, Andres M Lozano4,5, Clement Hamani2,5,15*

1. Neuroscience and Mental Health, Hospital for Sick Children Research Institute; Toronto, Canada 
2. Sunnybrook Research Institute; Toronto, Canada
3. Division of Neuroscience, Sírio-Libanês Hospital; São Paulo, Brazil
4. Division of Neurosurgery, Department of Surgery, University Health Network, Toronto, Canada
5. Division of Neurosurgery, Department of Surgery, University of Toronto; Toronto, Canada
6. Joint Department of Medical Imaging, University of Toronto; Toronto, Canada
7. Department of Functional and Stereotactic Neurosurgery, University Hospital San Vicente Fundación,
    Medellín, Colombia
8. Department of Functional and Stereotactic Neurosurgery, San Vicente Fundación, Rionegro, Colombia
9. Department of Neurosurgery, University Hospital La Princesa; Madrid, Spain
10. Nemod Research Group, Universidad Autónoma de Bucaramanga; Bucaramanga, Colombia
11. Division of Functional Neurosurgery, Department of Neurosurgery, FOSCAL Clinic; Bucaramanga,
      Colombia
12. LIM 23, Institute of Psychiatry, School of Medicine, University of São Paulo; São Paulo, Brazil
13. Department of Neurology, Integrated Clinic of Neuroscience, School of Medicine, University of São Paulo;
      São Paulo, Brazil.
14. Stereotactic and Functional Neurosurgery Division of the International Misericordia Clinic; Barranquilla,
     Colombia
15. Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre; Toronto, Canada
16. Department of Psychiatry, University of Toronto; Toronto, Canada
17. Servicio de Neuocirugia Funcional y Esterotaxia, Clinica Comuneros Bucaramanga, Clinica Desa y Clinica
      Dime Neurocardiovascular de Cali; Clinica Nueva del Lago, Bogota, Colombia.
18. Division of Neurosurgery, The Hospital for Sick Children; Toronto, Canada
19. Institute of Biomedical Engineering, University of Toronto; Toronto, Canada
20. Institute of Medical Science, University of Toronto; Toronto, Canada
† Flavia Venetucci Gouveia and Jürgen Germann contributed equally to this work and share first authorship.

* Corresponding Author: Dr. Flavia Venetucci Gouveia. Neuroscience and Mental Health, Hospital for Sick Children Research Institute. 686, Bay Street, Toronto, ON, M5G 0A4, Canada. [e-mail]
* Corresponding Author: Dr. Clement Hamani. Sunnybrook Research Institute. 2075 Bayview Ave, S126. Toronto, ON, M4N3M5, Canada. [e-mail]

It contains a zip folder ("estimated_binary_Volume_of_Tissue_Activated.zip") with one file (in nii.gz format) per patient estimating the Volume of Activated Tissue for that patient (the estimated 'reach' of the active DBS stimulation) and a demographics file.
The case numbers are identical to Table 1 in the manuscript.