cyp_p450_2d6_inhibition_veith_et_al

## Dataset Details

### Dataset Description

The CYP P450 genes are involved in the formation and breakdown (metabolism)
of various molecules and chemicals within cells. Specifically, CYP2D6 is primarily
expressed in the liver. It is also highly expressed in areas of the central
nervous system, including the substantia nigra.

- **Curated by:**
- **License:** CC BY 4.0

### Dataset Sources

- [corresponding publication](https://doi.org/10.1038/nbt.1581)
- [data source](https://tdcommons.ai/single_pred_tasks/adme/#cyp-p450-2d6-inhibition-veith-et-al)

## Citation

**BibTeX:**

```bibtex
@article{Veith2009,
doi = {10.1038/nbt.1581},
url = {https://doi.org/10.1038/nbt.1581},
year = {2009},
month = oct,
publisher = {Springer Science and Business Media LLC},
volume = {27},
number = {11},
pages = {1050--1055},
author = {Henrike Veith and Noel Southall and Ruili Huang and Tim James
and Darren Fayne and Natalia Artemenko and Min Shen and James Inglese
and Christopher P Austin and David G Lloyd and Douglas S Auld},
title = {Comprehensive characterization of cytochrome P450 isozyme selectivity
across chemical libraries},
journal = {Nature Biotechnology}
```

## 数据集详情

### 数据集描述
细胞色素P450（CYP P450）基因参与细胞内多种分子与化学物质的形成与分解（代谢过程）。具体而言，CYP2D6主要在肝脏中表达，同时在中枢神经系统的多个区域也呈高表达，包括黑质。

- **整理方：**
- **授权协议：** CC BY 4.0

### 数据集来源
- [相关研究论文](https://doi.org/10.1038/nbt.1581)
- [数据来源](https://tdcommons.ai/single_pred_tasks/adme/#cyp-p450-2d6-inhibition-veith-et-al)

## 引用信息

### BibTeX 引用格式
bibtex
@article{Veith2009,
doi = {10.1038/nbt.1581},
url = {https://doi.org/10.1038/nbt.1581},
year = {2009},
month = oct,
publisher = {施普林格科学与商业媒体有限公司},
volume = {27},
number = {11},
pages = {1050--1055},
author = {Henrike Veith and Noel Southall and Ruili Huang and Tim James
and Darren Fayne and Natalia Artemenko and Min Shen and James Inglese
and Christopher P Austin and David G Lloyd and Douglas S Auld},
title = {化学文库中细胞色素P450同工酶选择性的全面表征},
journal = {自然·生物技术（Nature Biotechnology)}
}