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The effect of PCN on gene expression in mouse primary hepatocytes

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106293
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The effect of prototypical pregnane receptor X (PXR) agonist (pregnenolone 16α-carbonitrile) PCN on hepatic gene expression was studied in mice primary hepatocytes. The effect of pregnenolone 16α-carbonitrile (PCN) was studied in male 9-week-old C57BL/6 mouse primary hepatocytes. Cells were treated with 10 μmol/l PCN for 12 h, DMSO was used as a control. Three parallel RNA samples were pooled in both groups. DNA microarrays we used for gene expression profiling.
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2018-01-27
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