Cryo-EM structure of RET/GFRa2/NRTN extracellular complex. The 3D refinement was applied with C2 symmetry.

Cryo-EM structure of RET/GFRa2/NRTN extracellular complex. The 3D refinement was applied with C2 symmetry. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ... Authors: Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. Deposit date: 2019-08-08 Release date: 2019-10-02 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.65 Å) Cite: Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019

RET/GFRa2/NRTN 细胞外复合物的冷冻电镜（Cryo-EM）结构。本数据集采用C2对称条件完成三维重构精修。描述项：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、钙离子（CALCIUM ION）、GDNF家族受体α-2（GDNF family receptor alpha-2）……作者：Li, J、Shang, G.J、Chen, Y.J、Brautigam, C.A、Liou, J、Zhang, X.W、Bai, X.C。提交日期：2019-08-08，发布日期：2019-10-02，最后修改日期：2024-10-23。实验方法：电子显微镜（ELECTRON MICROSCOPY），分辨率3.65埃（Å）。引用文献：《冷冻电镜分析揭示不同配体激活RET的共同机制与多样性》，刊载于《Elife》第8卷，2019年。