Members of an array of zinc finger proteins specify distict Hox chromatin boundaries [ChIP-seq]

In this experiment, we sought to identify how the distribution of RAD21 and ZNF263 change in WT, PATZ1 KO, and ZNF263 KO cells during differentiation of mouse embryonic stem cells (ESCs) into cervical motor neurons (MNs). Overall design: Examination of RAD21 and ZNF263 binding in embryonic stem cells and cervical motor neurons using ChIP-seq, by status of PATZ1 KO or ZNF263 KO in the cells: WT, ZNF263 KO, and PATZ1 KO