five

mouse CD8 T cells sequencing

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA812698
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Higher exchange efficiencies of peptide C8-3 and C9-7 to HLA-A*02:01 were observed by peptide exchange assay. To further validate the immunogenicity of a peptide, HLA-A2 transgenic mice were immunized with peptide C8-3 and C9-7, irrespectively. After the third immunization, splenic cells were harvested and cultured. peptide specific CD8 T cells were sorted with tetramer and sequenced.
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2022-03-04
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