Summary statistics for significant sex-differential pQTLs for antibody-based proteomic measurements in UK Biobank and aptamer-based proteomic measurements in Fenland study

Summary statistics for significant sex-differential pQTLs for Olink Explore 3072 measurements in UK Biobank and Somalogic measurements in Fenland study. The summary statistics contain approaximately 1 Mb region surrounding (±500 Kb on either side) the significant sex-differential pQTL. The regions were merged if there were multiple variants passing the significance threshold within close proximity. A proteome and genome-wide Bonferroni corrected significance threshold (phet<1.01x10-11 and phet<1.71x10-11 respectively for aptamer- [i.e. Somalogic] and antibody-based platforms [i.e. Olink Explore 3072]) for heterogeneity p-value was used to define sex-differential protein quantitative trait loci (i.e. sd-pQTLs). 

The file names for the files are as follows: {protein_target}_{chr}_{region_start}_{region_end}_{cohort}_proteomics_{sex_included_in_the_analysis}.txt

Corresponding author: Claudia Langenberg ([e-mail])