Data from: A curated and standardized adverse drug event resource to accelerate drug safety research

Identification of adverse drug reactions (ADRs) during the post-marketing
phase is one of the most important goals of drug safety surveillance.
Spontaneous reporting systems (SRS) data, which are the mainstay of
traditional drug safety surveillance, are used for hypothesis generation
and to validate the newer approaches. The publicly available US Food and
Drug Administration (FDA) Adverse Event Reporting System (FAERS) data
requires substantial curation before they can be used appropriately, and
applying different strategies for data cleaning and normalization can have
material impact on analysis results. We provide a curated and standardized
version of FAERS removing duplicate case records, applying standardized
vocabularies with drug names mapped to RxNorm concepts and outcomes mapped
to SNOMED-CT concepts, and pre-computed summary statistics about
drug-outcome relationships for general consumption. This publicly
available resource, along with the source code, will accelerate drug
safety research by reducing the amount of time spent performing data
management on the source FAERS reports, improving the quality of the
underlying data, and enabling standardized analyses using common
vocabularies.