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Role of ADAR1 and NOP14 on transcriptional output in cancer cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE275688
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The loss of ADAR1 significantly reduced ribosome production, decreased tumor translational efficiency, and impaired the translation of oncogenic pathways. And NOP14 significantly upregulated ribosome production and tumor translational efficiency. RNA-Seq was performed in control siRNA and ADAR1 siRNA cells. RNA-Seq was performed in NOP14-overexpressing and control MDA-MB-231 cells.
创建时间:
2025-08-05
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